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Tesamorelin Dosage Guide

September 30, 2025, Written By drugtextsite Leave a Comment

What is Tesamorelin?

Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH). It increases natural human growth hormone (HGH) release and is FDA-approved for body fat redistribution syndrome.

Research shows Tesamorelin may:

  • Reduce abdominal and visceral fat
  • Preserve lean muscle mass
  • Support nerve regeneration
  • Improve cognitive performance

It is not a steroid and does not affect testosterone levels.


Benefits of Tesamorelin

  • Burns fat in the abdomen and upper back
  • Targets visceral fat around organs such as the liver and intestines
  • Preserves and increases lean muscle mass
  • Boosts metabolism and daily energy levels
  • Improves insulin sensitivity and blood sugar control
  • Lowers cholesterol and triglycerides
  • Supports nerve repair and regeneration
  • Enhances brain performance and neurotransmitter function

Tesamorelin Side Effects

Common Side Effects

  • Injection site redness or swelling
  • Headache
  • Nausea
  • Muscle aches
  • Diarrhea
  • Sweating

Serious Side Effects (rare)

  • Diarrhea with fever and dehydration
  • Shortness of breath
  • Severe joint or muscle pain
  • Numbness or tingling in hands or feet
  • Increased risk of type 2 diabetes

Who Should Not Use Tesamorelin?

Avoid Tesamorelin if you:

  • Have a history of pituitary tumors or surgery
  • Have an active cancer
  • Are allergic to mannitol
  • Are pregnant or breastfeeding
  • Have hypothalamic-pituitary axis damage
  • Have a diagnosed pituitary disorder

Tesamorelin Reconstitution and Injection Instructions

  • Each vial contains 10mg Tesamorelin
  • Mix with 3mL (300 units) of bacteriostatic water
  • Administer as a subcutaneous injection

Tesamorelin Dosing Protocols

Standard Tesamorelin Dosing

  • 30 units = 1mg
  • Inject 30 units (1mg) once per day, 5 days per week

Maximum Tesamorelin Dosing

  • 60 units = 2mg
  • Inject 60 units (2mg) once per day, 5 days per week

Cycle Guidelines

  • Run a 12-week cycle followed by a 4-week break
  • Inject 5 consecutive days with 2 rest days
  • Dose at night, at least 90 minutes after your last meal

Tesamorelin Stacking Options

Fat Loss Stack

  • Tesamorelin + AOD-9604 + CJC-1295

Neuroregeneration Stack

  • Tesamorelin + SS-31 + MOTS-C

Aesthetic and Skin Stack

  • Tesamorelin + GHK-Cu + CJC-1295

Additional Synergistic Peptides

  • AOD-9604 – abdominal fat burning
  • CJC-1295 / Ipamorelin – higher GH release
  • GHK-Cu – tissue and skin regeneration
  • MOTS-C – metabolism and ATP boost
  • SS-31 – mitochondrial repair, nerve health
  • L-Carnitine – fat metabolism support

FAQ: Tesamorelin Dosing and Use

How do you inject Tesamorelin?

Tesamorelin is injected subcutaneously (under the skin). Most users inject in the abdomen area using an insulin syringe. Always follow proper reconstitution and injection protocols.

When is the best time to take Tesamorelin?

The best time is at night, at least 90 minutes after your last meal. This timing works with natural growth hormone release cycles.

How long should a Tesamorelin cycle last?

A standard cycle runs for 12 weeks, followed by a 4-week break to reset natural hormone sensitivity.

What is the standard Tesamorelin dose?

The standard dose is 1mg (30 units) per injection, 5 times per week. Advanced protocols may use 2mg (60 units).

Can Tesamorelin be stacked with other peptides?

Yes. It stacks well with peptides like AOD-9604 for fat loss, CJC-1295/Ipamorelin for growth hormone synergy, and GHK-Cu for skin and tissue health.

Does Tesamorelin affect testosterone?

No, Tesamorelin does not impact testosterone levels. It works by stimulating growth hormone release only.

What are the risks of Tesamorelin?

Possible risks include injection site irritation, muscle pain, nausea, and an increased chance of type 2 diabetes. More serious side effects are rare but possible.

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