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Semax

November 10, 2025 by drugtextsite Leave a Comment

Semax is a synthetic peptide that is an analog of adrenocorticotropic hormone (ACTH). It has been studied for its neuroprotective, cognitive-enhancing, and antidepressant effects. Semax stimulates the release of brain-derived neurotrophic factor (BDNF), a protein that promotes neuron growth and survival, and modulates neurotransmitter levels including dopamine, serotonin, and norepinephrine. It offers nootropic, neuroprotective, and neurorestorative benefits.


Benefits

  • Memory enhancement: Participants using Semax made 31% more correct responses than the control group on memory tests
  • Neuroprotection: Shields neurons from stroke, trauma, or neurodegenerative disease damage
  • Antidepressant effects: Reduces anxiety and depression in animal studies
  • Supports neuron survival and promotes synaptic growth and neuroplasticity
  • Helps neurons adapt to injury or environmental change
  • Protects the optic nerve and may be helpful for related disorders
  • Improves trophic supply of the brain (supports brain network connectivity)
  • May help manage ADHD symptoms
  • Inhibits enzymes that degrade enkephalins and regulatory peptides
  • May support recovery from opioid or alcohol withdrawal
  • Shows improvement in non-proliferative diabetic neuropathy
  • Potential for pain relief

Possible Side Effects

  • Headache
  • Nausea
  • Insomnia
  • Anxiety

Contraindications

  • Do not use if pregnant or breastfeeding
  • Not intended for individuals under 18

SEMAX: 10MG — RECONSTITUTION AND DOSING PROTOCOL

6-8 week cycle followed by 6-8 week washout period
Takes 2-3 weeks to build up in system to the point where Semax is operating at optimal capacity

Subcutaneous Administration


STANDARD PROTOCOL

Add 3mL (300 units) of BAC water

Weeks 3-4: 15 units, 1x/day, 5-7 days/week

Weeks 5-8: 30 units, 1x/day, 5-7 days per week

MAXIMUM PROTOCOL (for stroke or TBI recovery)

Add 1mL (100 units) of BAC water

10 day cycle: 60 units (6mg), 1x/day, for 10 days

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